Fecal microbiota transplantation for multiple organ dysfunction syndrome

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Fecal microbiota transplantation for multiple organ dysfunction syndrome

Approximately 40 trillion bacteria reside inside the human intestine, meaning there are at least as many cells of microbial origin as human origin [1]. While it was once believed that bacteria and humans simply coexisted in the same space, a wide body of evidence now suggests that host–microbial communication is more complex than ever imagined and the microbiome plays a critical role in maintai...

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Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis

BACKGROUND The dysbiosis of intestinal microbiota plays an important role in the development of gut-derived infections, making it a potential therapeutic target against multiple organ dysfunction syndrome (MODS) after sepsis. However, the effectiveness of fecal microbiota transplantation (FMT) in treating this disease has been rarely investigated. METHODS Two male patients, a 65-year-old and ...

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Fecal Microbiota Transplantation in Liver Diseases and Recent Developments

Introduction: The intestine, as an important part of the human gastrointestinal tract, provides a favorable milieu for the growth and development of a diverse and large population (approximately 1000 species) of bacteria. Currently, the presence of a cohesive relationship between intestinal bacteria and the host is being well studied and identified. According to the available scientific evidenc...

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Thomas J. Borody has a pecuniary interest in the Centre for Digestive Diseases, where fecal microbiota transplantation is a treatment option for patients and has filed patents in this area; Jordana Campbell has no financial interest or affiliation with any institution, organization, or company relating to the article. No support or funding, including pharmaceutical and industry support, was rec...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2016

ISSN: 1364-8535

DOI: 10.1186/s13054-016-1567-z